Working with Hazardous Substances

Hazardous substances are substances or mixtures that are potentially hazardous or harmful to humans or the environment. The aim of the tasks and measures realised by BAuA is to ensure the safe handling of chemicals and materials.

Man is filling chemicals in a large mixing tank
© Uwe Völkner, Fotoagentur FOX

Hazardous substances have specific physical, chemical or toxicological characteristics. For example, they may be highly flammable, poisonous, corrosive or carcinogenic.

To ensure the safe handling of hazardous substances, a series of laws, regulations, tasks and measures operate at the state, national and EU level as part of a complex risk management system.

Cover page of baua Guidance brief: "Hazardous Substances - Understanding their Classification and Labelling"

The leaflet "Hazardous Substances - Understanding their Classification and Labelling" gives an overview of the various hazard categories and the labels used on packaging for hazardous substances. It is intended for all individuals who handle hazardous substances..

Federal Office for Chemicals

The Chemicals Act (ChemG) appoints BAuA as the Federal Office for Chemicals (BfC) and, as such, as the statutory body for tasks under the REACH, CLP and Biocidal Products Regulations. In accordance with the key elements of the REACH Regulation, these tasks include the

  • registration,
  • evaluation,
  • authorisation and
  • restriction

of substances.

As part of the authorisation of biocidal products, the BfC is responsible for ensuring that biocides are only placed on the market if they can be handled safely. Active substances are evaluated and authorised in a two-stage process.
If substances are assigned to specific hazard classes, then specific measures usually apply to the use of these substances. Risk minimisation measures are chosen based on the results of extensive risk assessments and taking account of socio-economic factors, which can be estimated and evaluated using, for example, the "Socio-Economic Analysis (SEA)" instrument.

Easy-to-use workplace control scheme for hazardous substances

Practical guidance on risk assessment and the implementation of suitable protective measures are key prerequisites for protecting workers' health in activities involving hazardous sub-stances. In this context, it is important that hazards presented by hazardous substances can be identified quickly and associated with suitable protective measures. BAuA provides practical guidance in the form of the "Easy-to-use workplace control scheme for hazardous substances" (EMKG). The EMKG includes all potential hazards due to inhalation and skin contact as well as fire and explosion hazards. In a systematic approach companies are allowed to identify hazards associated with the handling of hazardous substances, as well as the correct measures to reduce exposure.

Biomonitoring

Biomonitoring is an important tool in occupational medicine for ensuring the safest possible design of work involving hazardous substances. It identifies individual forms of exposure, contributes to the assessment of working conditions and helps with the evaluation of occupational safety measures with a view to preventing health damage due to chemicals.

SUBSPORTplus portal about substitution of hazardous substances

Research Projects

Project numberF 2537 StatusOngoing Project Biomonitoring in exhaled air and effect monitoring of occupationally exposed styrene workers

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Research ongoing

Project numberF 2510 StatusOngoing Project Derivation of suitable biomonitoring methods to determine the current work-related lead exposure of employees

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Research ongoing

Project numberF 2493 StatusOngoing Project Modular Exposure Models for OSH Risk Assessment in Chemical Safety

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Research ongoing

Project numberF 2458 StatusCompleted Project Investigations into the feasibility of a cohort study among workers exposed to diisocyanates to accompany new regulations for diisocyanates under chemicals legislation

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Research completed

Project numberF 2484 StatusOngoing Project Packaging, formulations and systems for exposure reduction to hazardous substances in the workplace

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Research ongoing

Project numberF 2492 StatusCompleted Project Modular Exposure Models for OSH Risk Assessment in Chemical Safety

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Research completed

Project numberF 2487 StatusOngoing Project Validation of control guidance sheets for filling of containers with acids and bases

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Research ongoing

Project numberF 2486 StatusOngoing Project Determination of the inhalative exposure to hazardous substances and biological agents during the commercial use of gardening devices

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Research ongoing

Project numberF 2477 StatusCompleted Project Implementation of risk governance: meeting the needs of nanotechnology

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Research completed

Project numberF 2440 StatusOngoing Project Measures for control guidance sheets (MapS)

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Research ongoing

Project numberF 2430 StatusCompleted Project Collection of toxicokinetic data for the assessment of different exposure routes using the example of the antibiotic enrofloxacin

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Research completed

Project numberF 2410 StatusCompleted Project Determination of hazardous substances exposure during "Additive Manufacturing" – Application of powder-based systems

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Research completed

Project numberF 2404 StatusCompleted Project Study of the exposure to antibiotics of cattle hoof carers with biological monitoring

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Research completed

Project numberF 2403 StatusCompleted Project Validation of control guidance sheets for filling of containers with dust releasing solid matter

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Research completed

Project numberF 2366 StatusCompleted Project Human exposure to biocidal products: Measurement of inhalation and dermal exposure during the application of biocide foams

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Research completed

Project numberF 2365 StatusCompleted Project Development of an enforceable test method for determination of the rigidity of respirable biopersistent fibres

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Research completed

Project numberF 2346 StatusCompleted Project Polycyclic aromatic hydrocarbons - Implementation of the concept of exposure-risk-relationships in enterprises handling strong polluted materials

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Research completed

Project numberF 2314 StatusCompleted Project Easy-to-use workplace control scheme for hazardous substances 3.0 - Technical and didactical revision of the overall concept

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Research completed

Project numberF 2265 StatusCompleted Project Field Study on a Future Module "Fire and Explosion Risks" for an Easy-to-use Control Scheme for Hazardous Substances at the Workplace (EMKG)

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Research completed

Project numberF 2307 StatusCompleted Project Development and validation of control guidance sheets for protection against chemicals in maintenance and parking of cars

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Research completed

Project numberF 2309 StatusCompleted Project Validation of control guidance sheets for filling and emptying of containers for liquids

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Research completed

Publications

Search results

Toxic effects of various modifications of a nanoparticle following inhalation

Report 2013

This project aimed at comparing the toxic effects of the triple TiO2 UV TITAN M262, TiO2 UV TITAN M212 and TiO2 P25 coded in the …

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Characterisation of substances at nanoscale as background for the regulation in the framework of the regulation (EC) No. 1907/2006 (REACH)

Report 2013

The presented literature documentation shows the applicability of the test methods listed in regulation EC 440/2008. The first …

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Performance of test methods for checking the observance of acceptable and tolerable concentrations of carcinogenic substances, described with reference to the example of metals

Article 2013

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Health surveillance for workers exposed to beryllium and diagnostic procedures in beryllium-associated diseases

Article 2013

The complete article can be purchased in German at the website of the Journal "Deutsche medizinische Wochenschrift", Volume 138, …

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The nanotoxicology revolution

Article 2013

The complete article "The nanotoxicology revolution" can be downloaded at the website of the Journal "Archives of Toxicology", …

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Response to Morfeld (2013): Second commentary to Gebel 2012 - established use of cancer potency indices and biological plausibility

Article 2013

The complete article "Response to Morfeld (2013): Second commentary to Gebel 2012 - established use of cancer potency indices …

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Chronic obstructive pulmonary disease and longitudinal changes in pulmonary function due to occupational exposure to respirable quartz

Article 2013

The complete article "Chronic obstructive pulmonary disease and longitudinal changes in pulmonary function due to occupational …

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Re: Clinically significant lung function impairment due to current levels of respirable quartz? (authors' response)

Article 2013

The complete article "Re: Clinically significant lung function impairment due to current levels of respirable quartz? (authors' …

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Effects of single pesticides and binary pesticide mixtures on estrone production in H295R cells

Article 2013

The complete article "Effects of single pesticides and binary pesticide mixtures on estrone production in H295R cells" can be …

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Design and experimental evaluation of a new nanoparticle thermophoretic personal sampler

Article 2013

The complete article "Design and experimental evaluation of a new nanoparticle thermophoretic personal sampler" can be …

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Silica dust, radon and death from non-malignant respiratory diseases in German uranium miners

Article 2013

The complete article "Silica dust, radon and death from non-malignant respiratory diseases in German uranium miners" can be …

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Does inhalation of silica dust cause chronic renal disease? - A systematic review

Article 2013

The complete article "Does inhalation of silica dust cause chronic renal disease? - A systematic review" can be downloaded at …

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A thermal precipitator for the deposition of airborne nanoparticles onto living cells - Rationale and development

Article 2013

The complete article "A thermal precipitator for the deposition of airborne nanoparticles onto living cells - Rationale and …

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The risk-based concept for carcinogenic substances developed by the Committee on Hazardous Substances

Brochure 2013

After an intensive discussion between the social partners, labour inspectors of the Federal States and occupational accident …

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Reply to: Pesch B, Weiss T, Pallapies D, Schlüter G, Brüning T. Letter to the editor. Re: Seidler A, Jähnichen S, Hegewald J, Fishta A, Krug O, Rüter L, Strik C, Hallier E, Straube S. Systematic review and quantification of respiratory cancer risk for occupational exposure to hexavalent chromium

Article 2013

The complete article "Reply to: Pesch B, Weiss T, Pallapies D, Schlüter G, Brüning T. Letter to the editor. Re: Seidler A, …

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First Evaluation on the Joint Research Strategy of German Governmental Research Institutions "Nanotechnology - Risks related to Nanomaterials for Humans and the Environment" (2007 - 2011)

Cooperation 2013

This document presents a first review of over 80 projects on safety research in the field of nanotechnology that the …

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Diesel motor exhaust and lung cancer mortality: reanalysis of a cohort study in potash miners

Article 2013

The complete article "Diesel motor exhaust and lung cancer mortality: reanalysis of a cohort study in potash miners" can be …

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Dose determination of particles for air/liquid interface (ALI) technique for toxicity testing on human lung cells

Article 2013

The complete article "Dose determination of particles for air/liquid interface (ALI) technique for toxicity testing on human …

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Air/liquid interface (ALI) technique for toxicity testing of gaseous compounds on human lung cells

Article 2013

The complete article "Air/liquid interface (ALI) technique for toxicity testing of gaseous compounds on human lung cells" can be …

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Systematic review and quantification of respiratory cancer risk for occupational exposure to hexavalent chromium

Article 2013

The complete article "Systematic review and quantification of respiratory cancer risk for occupational exposure to hexavalent …

To the Publication

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