Biological Agents | Infection Control

Employees can be affected in various ways by biological hazards. The Federal Institute for Occupational Safety and Health (Bundesanstalt für Arbeitsschutz und Arbeitsmedizin, BAuA) contributes to the formulation of technical rules for activities involving biological agents. It also develops new measurement methodologies and researches health risks and appropriate protective measures.

Employees in protective clothing in the laboratory
© iStock | RyanKing

Essentially, a risk is present as soon as an activity requires the handling of biological agents, for instance in laboratories, the healthcare sector, veterinary facilities, or the waste management industry.

Natural outbreaks of infectious diseases, sometimes on a pandemic scale, can raise the risk of infection among employees performing many different kinds of activity as well. Other biological agents may not be infectious, but can trigger sensitising or toxic reactions.

In order to ensure employees working with biological agents benefit from cutting-edge protection, our experts on the Committee on Biological Agents (Ausschuss für Biologische Arbeitsstoffe, ABAS) help keep the Technical Rules for Biological Agents (Technische Regeln für Biologische Arbeitsstoffe, TRBAs) up to date. Researchers at BAuA develop new measurement methodologies and assessment tools. Furthermore, they conduct systematic field research into bioaerosols in the workplace with the aim of preventing airborne transmission. And BAuA is preparing for future pandemics by researching both work-related infection risks and suitable protective measures.

It is hoped the results will enable organisations to correctly assess the risks to their employees from biological agents and infectious diseases, then take suitable protective measures, putting in place appropriate plans and precautions for every eventuality.

Research Projects

Project numberF 2584 StatusOngoing Project Consideration of humans as a bioaerosol source for infection control in the workplace - Quantification of proteins in exhaled air

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Research ongoing

Project numberF 2583 StatusOngoing Project Investigation of the size distribution of exhaled particles in temporal relation to mask use

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Research ongoing

Project numberF 2562 StatusOngoing Project Occupational COVID-19 exposure and infection risks: Analyses based on the Gutenberg COVID-19 Study.

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Research ongoing

Project numberF 2545 StatusCompleted Project Work related investigation of the rate of SARS-CoV-2 infected and Post-COVID symptomatic people based on data of the health authorities in Thuringia

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Research completed

Project numberF 2547 StatusOngoing Project Determination of exposure during phage application in pig barns

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Research ongoing

Project numberF 2546 StatusOngoing Project Characterisation of bioaerosols in the fine dust fraction of indoor air

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Research ongoing

Project numberF 2509 StatusOngoing Project Relative quantification of proteins in cell culture system exposed to biological agents by mass spectrometry

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Research ongoing

Project numberF 2491 StatusOngoing Project Assessment and evaluation of the toxic potential of biological agents on the basis of respiratory tract-related in vitro models: Subproject II: Development of an exposure system for the assessment of volatile metabolites of biological agents

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Research ongoing

Project numberF 2489 StatusCompleted Project Assessment of health effects by bioaerosols in case of mould

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Research completed

Project numberF 2486 StatusOngoing Project Determination of the inhalative exposure to hazardous substances and biological agents during the commercial use of gardening devices

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Research ongoing

Project numberF 2470 StatusCompleted Project Biomonitoring of workers´ exposure to mycotoxins

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Research completed

Project numberF 2441 StatusCompleted Project Analysis of bioaerosol-borne toxins by proteomics technologies

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Research completed

Project numberF 2426 StatusCompleted Project Molecular differentiation of living and dead biological agents and detection of the tenacity of airborne biological agents

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Research completed

Project numberF 2383 StatusCompleted Project Detection of airborne biological agents under difficult analytical conditions - background measurement and exclusion of inhibitory substances

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Research completed

Project numberF 2356 StatusCompleted Project Exposure of hatchery workers to airborne bacteria under consideration of existing antibiotic resistances

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Research completed

Project numberF 2350 StatusCompleted Project A model system of lung cells for investigation of bacterial pathogenicity

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Research completed

Project numberF 2331 StatusCompleted Project Antibiotic-resistant bacteria in emissions from the industrial livestock farming

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Research completed

Project numberF 2330 StatusCompleted Project Exposure to biological agents at biogas production

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Research completed

Publications

Search results

(In)equality at the workplace? Differences in occupational safety and health measures during the COVID-19 pandemic and related employee health

Article 2023

The complete article "(In)equality at the workplace? Differences in occupational safety and health measures during the COVID-19 …

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Authors' response: Occupation and SARS-CoV-2 infection risk among workers during the first pandemic wave in Germany: potential for bias

Article 2022

This article is published in the "Scandinavian Journal of Work, Environment and Health" (2022).

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BAuA recommendations for action on SARS-CoV-2

baua: Fokus 2022

The BAuA recommendations for action on SARS-CoV-2 are intended to provide guidance on when infection protection measures should …

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In Vitro Systems for Toxicity Evaluation of Microbial Volatile Organic Compounds on Humans: Current Status and Trends

Article 2022

Microbial volatile organic compounds (mVOC) are metabolic products and by-products of bacteria and fungi. They play an important …

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Increases in health problems during the first pandemic wave - An analysis of occupational differences based on the German National Cohort (NAKO)

Article 2022

The complete article "Increases in health problems during the first pandemic wave - An analysis of occupational differences …

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Increases in health problems during the first pandemic wave - An analysis of occupational differences based on the German National Cohort (NAKO)

Article 2022

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Occupation and SARS-CoV-2 infection risk among 108 960 workers during the first pandemic wave in Germany

Article 2022

Objective: The aim of this study was to identify the occupational risk for a SARS-CoV-2 infection in a nationwide sample of …

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Occupation and SARS-CoV-2 infection risk among 108 960 workers during the first pandemic wave in Germany

Article 2022

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Target Mechanisms of the Cyanotoxin Cylindrospermopsin in Immortalized Human Airway Epithelial Cells

Article 2022

Cylindrospermopsin (CYN) is a cyanobacterial toxin that occurs in aquatic environments worldwide. It is known for its delayed …

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A risk estimate of a SARS-CoV-2 coronavirus infection among grocery and drugstore retail employees

baua: Fokus 2021

Approximately 780,000 employees work in grocery and drugstore retail in Germany. Due to its systemic relevance, this sector was …

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Analysis of the COVID-19 risk by occupational groups and industry in Germany

Article 2021

The complete article can be purchased in German at the website of the Journal "Arbeitsmedizin, Sozialmedizin, Umweltmedizin", …

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Application of impedance measurement to investigate in vitro inhalation toxicity of bacteria

Article 2021

Background: Workers of agriculture and intensive life stock farming are exposed to highly contaminated workplaces. Bioaerosol …

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Endotoxin measurements in the PM10 fraction of ambient air

Article 2021

As part of the outer cell wall of gram-negative bacteria endotoxins can be found ubiquitous in nature. So far most studies on …

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Evaluation of occupational health and safety measures during the SARS-CoV-2 pandemic

baua: Report 2021

The Corona Pandemic is a major challenge for companies for more than a year. In order to continue business and reduce the risk …

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Evaluation of optical aerosol spectrometers for the determination of workplace and corona-relevant aerosols

Article 2021

Optical aerosol spectrometers have become popular for time-resolved determination of ex-posure to respirable dust in workplaces …

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Multiplexed Workplace Measurements in Biogas Plants Reveal Compositional Changes in Aerosol Properties

Article 2021

Anaerobic digestion is an emerging technology producing energy from renewable resources or food waste. Exposure screenings, …

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Occupational safety and health in Germany during the Corona crisis

baua: Report brief 2021

German companies had to face up to a number of organisational and economic challenges as a result of the Coronavirus pandemic. …

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Quantification of DNA in PM10 fraction of aerosols from rural ambient air

Article 2021

Although existing guidelines and standards for measurement of biotic components in Germany are dominated by cultivation …

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Stigmatization from Work-Related COVID-19 Exposure: A Systematic Review with Meta-Analysis

Article 2021

Stigmatization from work-related COVID-19 exposure has not been investigated in detail yet. Therefore, we systematically …

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The COVID-19 Working Time Ordinance: Implications for occupational safety and health and insights from an employer survey

Article 2021

The complete article can be purchased in German at the website of the Journal "Arbeitsmedizin, Sozialmedizin, Umweltmedizin", …

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Well protected at work? Occupational safety and health in the Corona pandemic from the employees' point of view

baua: Report brief 2021

For over a year, the Corona pandemic has presented companies and employees with special challenges in the development and …

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Working from home even after the coronavirus pandemic? Advantages and disadvantages from a business perspective

Article 2021

The complete article can be purchased in German at the website of the Journal "Arbeitsmedizin, Sozialmedizin, Umweltmedizin", …

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Working from home in the corona crisis: What's next?

baua: Report brief 2021

During the corona crisis, and especially during the period of strict lockdown, many companies have used working from home to …

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Benchmarking the MinION: Evaluating long reads for microbial profiling

Article 2020

Nanopore based DNA-sequencing delivers long reads, thereby simplifying the decipherment of bacterial communities. Since its …

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Differences in COVID-19 risk between occupational groups and employment sectors in Germany

Article 2020

The complete article can be purchased in German at the website of the Journal "Deutsches Ärzteblatt", olume 117, Issue 38, pp. …

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SARS-CoV2 and stigmatization in association with work: A scoping review

Preprint 2020

The complete preprint "SARS-CoV2 and stigmatization in association with work: A scoping review" can be downloaded at the website …

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Bioaerosols: From measurement to assessment

Article 2019

The complete article "Bioaerosols: From measurement to assessment" can be downloaded at the website of the Journal "

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Occupational Exposure to Antibiotics in Poultry Feeding Farms

Article 2019

The complete article "Occupational Exposure to Antibiotics in Poultry Feeding Farms" can be downloaded at the website of the …

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Development of a methodological approach for the characterization of bioaerosols in exhaust air from pig fattening farms with MALDI-TOF mass spectrometry

Article 2017

In this paper, we evaluated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) as a …

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Hatchery workers' IgG antibody profiles to airborne bacteria

Article 2017

The complete article "Hatchery workers' IgG antibody profiles to airborne bacteria" can be downloaded at the website of the …

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