In order to carefully weigh the most appropriate risk management measures for a substance under REACH, all available information has to be considered. Especially in the context of substances and technologies also used in energy transition, it is of importance to consider also potentially conflicting goals on a European level. The research project generated a list of substances that are both relevant for energy transitions and are potentially subject for regulatory measures under REACH, in order to identify the necessity of a detailed risk management analysis at an early stage.